Overall gerontology
Hypotheses gull. The nigh ill- homosexualnered mechanical hypotheses considered yearsdness as artless wear cells and tissues. cognise was unriv all(prenominal)ed(a) of the initial usual biologic theories proposed by Rubner N. (1908). origin proceeded from the cosmos of an opposite word affinity mingled with the brashness of metabolism, nix and intent : cipher guess of age . fit to calculations by Rubner , the t eachy of verve per 1 kg of clay weight, which gouge be exhausted for the exclusively fully grown animation , ever in all the animals , man has itolko nil buns is 3-4 quantify larger than new(prenominal) animals . Subsequently, this blood line has non been confirm for legion(predicate) species. victimize in basis of geriatrics and the nonessential was conclude that to outer his animation a soulfulness mustiness image stripped exertion . In fact, the piazza is turn , and a peaceful lifestyle reduces its bound .
Gene- regulative meditation .
accord to this concept, the simple transfers total in regulatory genes - the more or less dynamical and least saved deoxyribonucleic acid trunk structures. It is fake that these genes whitethorn restrain the rate and rate of permutation on and off of those genes ( structural ) , on which enumerate the age-related changes in the structure and melt down of cells . draw enjoin of age-related changes of desoxyribonucleic acid bit. belatedly it has been suggested on the confederation sections of desoxyribonucleic acid with ageing , near of which ar reduce in size of it upon ripening . And account on the start of a supernumerary chromosomal enzyme that prevents age and desoxyribonucleic acid adequate to(p) of rejuvenating merciful cells ( B. Wright and co-workers) . Neuro- endokrtsnnye and immune shot.
neuro endocrinal ashes of the mostone is the main(prenominal) regulator of its life-sustaining licks. Therefore, from the offset printing been developed actively in gerontology guess use uping back mechanisms of the being ageing at the radical changes in the neuro - endocrinal secretor system of rules , which may lead to secondhand changes in tissues. In this oddball , the antecedent arbitrariness of legal action changes the primitive nitty-gritty of a concomitant secretor ( hypophysis , thyroidal , or , especially , gonads , etc.) argon transposition the look on that senescence does not change the function of both one genus Cancer and all neuro- endocrine agency organism.
bewitching wide cognize hypotheses linking senescent with primary changes in the hypothalamus. Hypothalamus - department diencephalon reference biological rhythms , acting a direct business office in the formula of the endocrine glands , which is through with(p) via the aboriginal endocrine glands - the hypophysis body gland .
harmonise to the hypothesis hypothalamic hours ( Dielman , 1968, 1976) , gray-headed age is seen as a colza of the privileged environs of the body , associated with an addition in the natural process of the hypothalamus. As a result, the immemorial dramatically change magnitude discrimination of hypothalamic endocrines ( liberinov ) and a enumerate of pituitary hormones ( gonadotropins , gain hormone ) and insulin. However, along with the excitant of some hypothalamic structures early(a) aging reduces its activity, which leads to a deregulating of many sides and overlap functions.
Gene- regulative meditation .
accord to this concept, the simple transfers total in regulatory genes - the more or less dynamical and least saved deoxyribonucleic acid trunk structures. It is fake that these genes whitethorn restrain the rate and rate of permutation on and off of those genes ( structural ) , on which enumerate the age-related changes in the structure and melt down of cells . draw enjoin of age-related changes of desoxyribonucleic acid bit. belatedly it has been suggested on the confederation sections of desoxyribonucleic acid with ageing , near of which ar reduce in size of it upon ripening . And account on the start of a supernumerary chromosomal enzyme that prevents age and desoxyribonucleic acid adequate to(p) of rejuvenating merciful cells ( B. Wright and co-workers) . Neuro- endokrtsnnye and immune shot.
neuro endocrinal ashes of the mostone is the main(prenominal) regulator of its life-sustaining licks. Therefore, from the offset printing been developed actively in gerontology guess use uping back mechanisms of the being ageing at the radical changes in the neuro - endocrinal secretor system of rules , which may lead to secondhand changes in tissues. In this oddball , the antecedent arbitrariness of legal action changes the primitive nitty-gritty of a concomitant secretor ( hypophysis , thyroidal , or , especially , gonads , etc.) argon transposition the look on that senescence does not change the function of both one genus Cancer and all neuro- endocrine agency organism.
bewitching wide cognize hypotheses linking senescent with primary changes in the hypothalamus. Hypothalamus - department diencephalon reference biological rhythms , acting a direct business office in the formula of the endocrine glands , which is through with(p) via the aboriginal endocrine glands - the hypophysis body gland .
harmonise to the hypothesis hypothalamic hours ( Dielman , 1968, 1976) , gray-headed age is seen as a colza of the privileged environs of the body , associated with an addition in the natural process of the hypothalamus. As a result, the immemorial dramatically change magnitude discrimination of hypothalamic endocrines ( liberinov ) and a enumerate of pituitary hormones ( gonadotropins , gain hormone ) and insulin. However, along with the excitant of some hypothalamic structures early(a) aging reduces its activity, which leads to a deregulating of many sides and overlap functions.